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Yan Yang, Ph.D, Prof.

Principal Investigator
State Key Laboratory of Brain & Cognitive Sciences, IBP


Research Interests: Neural mechanisms underlying motor learning and control


Email: yyang@ibp.ac.cn


Tel: 010-64886521


Address: 15 Datun Road, Chaoyang District, Beijing, 100101, China


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Biography

2002 - 2007 Institute of Biophysics, Chinese Academy of Sciences, Ph.D.

2007 - 2009 University of California, San Francisco, Postdoctoral Scientist

2012 - 2016 Duke University School of Medicine, Research Associate

2016 - Institute of Biophysics, Chinese Academy of Sciences, Professor

2018 Supported by the National Natural Science Foundation of Excellent Youth Scholar

Awards
Membership in Academies & Societies
Research Interests

The precision of movement is key for humans and animals to protect the interests of themselves and their kin. How can we use sensory to make accurate and precise movements? How do neural circuits implement these impressive capabilities? How do we learn and perfect movements? All these could be summarized as a key question:How perception guides action?

Our brain acquires sensory information from external circumstances and generates an appropriate behavioral response. The ability varies considerably among individuals. It depends on multiple facets: reward, motivation, age etc., which make the key question an appealing topic for understanding brain functions. To advance the knowledge, we aim to quantitatively analyze movements and neuronal activities, decode their relationships, and apply brain modulation approaches to test cause-and-effect function in health and diseases.

Grants
Selected Publications

1. Tong Xiao; Kaijie Wu; Peiliang Wang; Yali Ding; Xiao Yang; Chao Chang*;Yan Yang*. (2023). Sensory input-dependent gain modulation of the optokinetic nystagmus by mid-infrared stimulation in pigeons,eLife, 78729.https://doi.org/10.7554/eLife.78729. (* Corresponding authors).

2. Lasse Knudsen; Christopher J. Bailey; Jakob U. Blicher;Yan Yang; Peng Zhang; Torben E. Lund. (2023). Improved sensitivity and microvascular weighting of 3T laminar fMRI with GE-BOLD using NORDIC and phase regression,NeuroImage,https://doi.org/10.1016/j.neuroimage.2023.120011.

3. Huang Wang, Xiaoxiao Wang, Yanming Wang, Du Zhang,Yan Yang, Yifeng Zhou, Bensheng Qiu, Peng Zhang. (2023). White matter BOLD signals at 7 Tesla reveal visual field maps in optic radiation and vertical occipital fasciculus.NeuroImage, 269, 119916.https://doi.org/10.1016/j.neuroimage.2023.119916.

4. Huixi Dou, Huan Wang, Sainan Liu, Jun Huang, Zuxiang, Liu, Tiangang Zhou,Yan Yang*. (2023). Form properties of moving targets bias smooth pursuit target selection in monkeys.Neuroscience Bulletin,https://doi.org/10.1007/s12264-023-01022-z. (* Corresponding author).

5. Xiaohui Wang, Xiaoli Cui, Yang Li, Fei Li, Yue Li, Jinye Dai, Han Hu, Xuefeng Wang, Jianyuan Sun,Yan Yang*, Shuli Zhang. (2022). MC4R deficiency causes postsynaptic transmission dysregulation as a crucial culprit for obesity.Diabetes,https://doi.org/10.2337/db22-0162.

6. Xiaoli Cui, Ruijin Zhang, Ye Yang, Erzhong Wu, Yiheng Tang, Zhihua Zhao, Chao Li, Lei Yang, Xueyi Teng, Yanzhen Ye, Ya Cui, Feng Xu, Zewen Su, Dongpeng Wang, Dongdong Zhang,Yan Yang, Jianyuan Sun, Jianjun Luo, Shuli Zhang, Runsheng Chen, and Jianzhong Jeff Xi. (2022). Identification and characterization of long non-coding RNA Carip in modulating spatial learning and memory.Cell Reports, 38, Feb. 22,https://doi.org/10.1016/j.celrep.2022.110398.

7. Nathan J. Hall,Yan Yang, and Stephen G. Lisberger, (2018) Multiple components in direction learning in smooth pursuit eye movements of monkeys.Journal of Neurophysiology, 120(4):2020-2035. doi: 10.1152/jn.00261.2018.

8.Yan Yang, Qian Wang, Shu-rong Wang, Yi Wang and Qian Xiao, (2017) Representation of time interval entrained by periodic stimuli in the visual thalamus of pigeons.eLife; 6:e27995. doi:https://doi.org/10.7554/eLife.27995.

9.Yan Yang*, Stephen G. Lisberger, (2017) Modulation of complex-spike duration and probability during cerebellar motor learning in visually guided smooth-pursuit eye movements of monkeys.eNeuro, 10;4(3). doi: 10.1523/ENEURO.0115-17.2017. (*Corresponding author).

10. Jun Huang,Yan Yang, Ke Zhou, Xudong Zhao, Quan Zhou, Hong Zhu, Yingshan Yang, Chunming Zhang, Yifeng Zhou and Wu Zhou. (2017) Rapid processing of a global feature in the ON visual pathways of behaving monkeys.Frontiers in Neuroscience,perception science, 25;11:474. doi: 10.3389/fnins.2017.00474.

11.Yan Yang*,Stephen G Lisberger*, (2014) Purkinje-cell plasticity and cerebellar motor learning are graded by complex-spike duration.Nature, 510(7506):529-32.(* Corresponding authors).

12.Yan Yang*,Stephen G Lisberger, (2014) Role of plasticity at different sites across the time course of cerebellar motor learning.Journal of Neuroscience,34(21):7077-90.(* Corresponding author).

13.Yan Yang, Stephen G Lisberger, (2013) Interaction of plasticity and circuit organization during the acquisition of cerebellum-dependent motor learning.eLife, 2(0): e01574.

14.Yan Yang, Stephen G Lisberger, (2010) Learning on multiple timescales in smooth pursuit eye movements.Journal of Neurophysiology, 104(5):2850-62.

15.Yan Yang, Peng Cao, Yang Yang, Shu-Rong Wang, (2008) Corollary discharge circuits for saccadic modulation of the pigeon visual system.Nature Neuroscience, 11(5):595-602.

( Evaluated by Faculty of 1000 ).

16. Yang Yang,Yan Yang, Shu-Rong Wang, (2008) Neuronal circuitry and discharge patterns controlling eye movements in the pigeon.Journal of Neuroscience, 15; 28(42):10772-80.

(From Yan Yang, March 17, 2023)

Contact Us

Tel: 010-64889872

E-Mail: webadmin@ibp.ac.cn

Address: No 15 Datun Road, Chaoyang District, Beijing

Postcode: 100101

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